Comparison tool

Compare peptides

Half-life, dosing, mechanism, stability — side by side. Select up to four compounds.

GLP-1 ComparisonNext-Gen GLP-1sOral vs InjectableHealing StackCognitive EnhancementGrowth Hormone StackPeptide Blends

Property	Semaglutide	Tirzepatide	Retatrutide
Category	glp1	glp1	glp1
Type	peptide	peptide	peptide
Mechanism	GLP-1 receptor agonist	Dual GLP-1/GIP receptor agonist	Triple agonist (GLP-1/GIP/Glucagon)
Research Stage	fda-approved	fda-approved	research
Dosing Range	0.25-2.4mg weekly	2.5-15mg weekly	1-12mg weekly
Frequency	Once weekly	Once weekly	Once weekly
Half-Life	~7 days	~5 days	~6 days
Bioavailability / Route	Subcutaneous	Subcutaneous	Subcutaneous
Onset Time	2-4 weeks for appetite reduction	2-4 weeks for appetite reduction	2-4 weeks
Key Benefits	Weight managementType 2 diabetesAppetite control	Weight managementType 2 diabetesMetabolic health	Weight managementMetabolic optimization
Key Risks	NauseaVomitingDiarrheaConstipation	NauseaDiarrheaDecreased appetiteVomiting	NauseaDiarrheaVomiting
Storage	Refrigerated (2-8°C)	Refrigerated (2-8°C)	Refrigerated (2-8°C)

Property comparison · Radar

Duration

Quick Onset

Versatility

Tolerability

Use Cases

Stackability

Typical dose ranges